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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: A novel pH-sensitive nanoparticles encapsulating anti-PD-1 antibody and MDK-siRNA overcome immune checkpoint blockade resistance in HCC via reshaping immunosuppressive TME

Fig. 1

Inhibition of M2 Macrophage Polarization by MDK-siRNA. (A-B) MDK-siRNA suppresses M2 polarization markers (Arg1 and CD206) in macrophages. (C) Quantitative RT-PCR analysis of Arg1, CD206, CD80, and iNOS mRNA levels in macrophages. (D) Western blot analysis of Arg1, CD206, CD80, iNOS, and IL-6 protein expression in macrophages treated with various MDK-siRNA constructs

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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