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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Digital PCR-based genetic profiling from vitreous fluid as liquid biopsy for primary uveal melanoma: a proof-of-concept study

Fig. 3

(A) Analysis of Gαq signalling mutations using targeted digital PCR, here exemplified for the measurement of GNA11 p.Q209L mutant and wild-type DNA alleles with two representative two-dimensional plots for a vfDNA+/UM− and vfDNA+/UM+ sample. The colour of the cluster indicates the content of the digital PCR droplets (grey: no target DNA, blue: mutant DNA, green: wild-type DNA, orange: wild-type and mutant DNA). (B) Comparison of non-melanoma cell-derived DNA concentrations in vfDNA+/UM− and vfDNA+/UM+ samples.

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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